|
Trade Name：Metoclopramide, Paspertin, Maxolon, Primperan
Chemistry Name：2-Methoxy-4-amino-5-chloro-N-(β-diethylaminoethyl)-benzamide
Molec ular formula： C14H22ClN3O2 299.80
Physical and Chemical Properties：white crystallize Powder; Have no to smell, and the flavor is bitter.The is in the chloroform, in the ether or acetone inside slightly , in the B ether very tiny deliquescence, in the water and almost not ;Fuse in the acidity aqua.The of this orders to 145-147 ℃.
Purpose：The antiemetic medicine.Used for the variety to vomit.The pregnant woman forbids to use.
Quality standards：EP4, JP13, CP2000。
| Items |
EP5 |
CP2005 |
JP14 |
| Appearance |
A white or almost white, fine powder |
A white or almost white, fine powder |
A white or almost white, fine powder |
| Appearance of solution |
Y6 |
Clear |
Clear |
| Melting point |
|
147-151℃ |
146-149℃ |
| Identification |
Positive |
Positive |
Positive |
| Loss on drying |
≤1.0% |
≤0.5% |
≤0.5% |
| Arsenic |
|
|
≤2ppm |
| Heavy metals |
≤20ppm |
≤20ppm |
≤20ppm |
| Sulphated ash |
≤0.1% |
≤0.1% |
≤0.1% |
| Content |
99.0~101.0% |
99.0~101.0% |
≥99.0% |
Related substances
（HPLC） |
Any impurity: NMT 0.2% |
≤0.5% (TLC) |
|
| Total impurities: NMT0.6% | |
