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Trade Name：Metoclopramide Hydrochloride
Chemistry Name：2-Methoxy-4-amino-5-chloro-N-(β-diethylaminoethyl)-benzamide Hydrochloride
Molecular formula：C14H22ClN3O2 ,HCl,H2O
Molecular weight ：354.30
Physical and Chemical Properties：White or almost white crystallize powder or crystal, easyis in the water and ether, tiny in four chlorination carbon, scarcely is in the B ether.At 183 ℃ are or so to melt to resolve at the same time.
Purpose：The antiemetic medicine.Used for the variety to vomit.The pregnant woman forbids to use.
Quality standards：BP98, USP29, EP5。
| Items |
BP2003 |
USP29 |
EP5 |
| Appearance |
white or almost white, crystalline powder or crystals |
|
white or almost white, crystalline powder or crystals |
| Appearanceof solution |
Clear and colourless |
|
Clear and colourless |
| Identification |
Positive |
Positive |
Positive |
| Water |
4.5~5.5% |
4.5~6.0% |
4.5~5.5% |
| Heavy metals |
≤20ppm |
|
≤20ppm |
| Sulphated ash |
≤0.1% |
≤0.1% |
≤0.1% |
| Content |
99.0~101.0% |
99.0~101.0% |
99.0~101.0% |
| Related substances |
Any impurity: NMT 0.5% (HPLC) |
Any impurity: NMT 0.5%Sum of all impurity: NMT 1.0%(TLC) |
Any impurity: NMT 0.5% (HPLC) |
| Organic volatile impurities |
|
Nothing |
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